The Best Baby Wipes for Clearing Up Diaper Rash

Baby wipes are a convenient way to clean baby’s soft skin, but not all are suitable for use on diaper rash. Help protect baby’s skin with wipes that won’t cause irritation.


As moms, we want the very best for our babies. While you can’t always avoid all chemicals, you can make the executive decision to reduce the amount of harmful ingredients you expose your child to. Certain types of baby wipes contain hidden ingredients known to contribute to or worsen diaper rash.

Components like fragrances can irritate baby’s sensitive skin. Parabens, a chemical preservative, have been found to mimic the female hormone estrogen. Some baby wipes even contain ingredients known to cause skin irritation, such as ethylhexylglyerin, benzyl alcohol, polysorbate 20, and glycol.

“When choosing a wipe, make sure you look for a brand that is alcohol-free so that it doesn’t dry or sting skin and that is paraben-free and free from potential irritating preservatives such as MI,” says Dr. William Sears.

If your baby has diaper rash, take a close look at the wipes you’ve been using. To avoid further irritation, switch to a natural wipe free of irritating chemicals and hidden ingredients. Ideally, baby wipes should be hypoallergenic, perfume-free, and targeted for sensitive skin.

Best Wipes for Diaper Rash

Features to Look For

When your baby has a diaper rash you want to do everything in your power to clear it up quickly and with the least amount of discomfort possible. The right type of wipes will keep your little one’s skin clean without contributing to further skin irritation. Learn what features to look for in baby wipes for diaper rash.

Natural Ingredients

Your baby’s skin is delicate. To avoid irritation, choose a wipe that contains natural ingredients. Chemicals and harsh additives can cause skin to redden and become easily irritated. There are several great brands on the market that offer the perfect balance of natural ingredients and good cleaning power.


If your wipes are tearing or breaking during standard diaper changes, you need a more resilient wipe. A more durable wipe will allow you to clean your baby’s skin in just one or two passes. Using inferior wipes requires you to wipe the skin more frequently, which can contribute to diaper rash.

Material and Texture

When your baby has a diaper rash, you want to be cautious when cleaning the skin. To help avoid discomfort, use a soft wipe that feels gentle on the skin. Baby wipes should have just the right amount of moisture. Too dry and you risk irritating the skin, but too wet and you may experience dripping and an overall messier diaper change.

Pampers Natural Clean Wipes

Best Wipes for Diaper Rash Pampers

For a high-quality wipe without all the bells and whistles, you can’t go wrong with Pampers Natural Clean Wipes. This package of seven refill packs comes in at just under $12, making each wipe just $0.02.

Mom Love Best calls them the ‘Best Baby Wipes for Newborns’ as they are hypoallergenic and do not contain perfumes that will irritate your baby’s skin. Compared to the leading U.S. sub-brand, these wipes are four times stronger and feature a soft grip texture for a gentle and efficient clean.

If your little one whimpers during diaper changes due to a rash, you need a wipe that will help heal the skin. Pampers Natural Clean Baby Wipes contain lotion, natural aloe, and a touch of vitamin E which help to nourish and protect baby’s delicate skin.

Things to Keep in Mind

These baby wipes come in soft packages. If you prefer the convenience of reusable tubs, you can easily transfer the wipes into a wipe dispenser.

Who’s it Best for?

Pampers Natural Clean Baby Wipes are an excellent choice for parents who desire a strong, unscented wipe that won’t irritate the skin.

Seventh Generation Thick & Strong Free and Clear Baby Wipes

Best Wipes for Diaper Rash Seventh Gen

Seventh Generation wipes are known for their Free & Clear properties, meaning unscented and free of dyes, parabens, phthalates, and synthetic fragrances. The Seventh Generation Thick & Strong Free and Clear Baby Wipes offer these and many other benefits, making them an excellent choice for babies with diaper rash.

Designed for baby’s sensitive skin, these soft and thick wipes are safe for use on the face, hands, and diaper rash area. The wipes are hypoallergenic, dermatologist-tested, and get their strength from wood pulp, a renewable resource.

For just under $15, you’ll receive six wipe packages for a total wipe count of 384. This makes each wipe just $0.04.

Things to Keep in Mind

These Seventh Generation Baby Wipes come in soft packages that do not reseal, putting them at risk for prematurely drying out. You can prevent this from happening by transferring the wipes to a wipe dispenser or keeping them inside a Zip-Lock bag.

Who’s it Best for?

If you prefer to buy your baby wipes in bulk and want a natural product free of alcohol, dyes, parabens, phthalates, and synthetic fragrances, Seventh Generation wipes are a great option.

Pampers Sensitive Baby Wipes

Best Wipes for Diaper Rash Pampers Sensitive

It’s referred to as the ‘#1 choice of hospitals’ based on hospital sales data, as well as the ‘#1 sensitive wipe’ based on U.S. and Canada “Sensitive” nationally branded sales. Pampers Sensitive Baby Wipes are clinically proven mild and provide a gentle clean for diaper rash and everyday diaper changes.

“Just like its Swaddlers diapers are made to cover tiny bottoms, Pampers Sensitive wipes are best for your newborn’s delicate skin,” says Best Products. “The mild formula is hypoallergenic and perfume-free, plus it restores your baby’s natural pH with each swipe.”

For just under $12, you’ll receive seven refill packs which equate to just $0.03 per wipe. Pampers Baby Sensitive Wipes are 20 percent thicker than regular Pampers wipes and contain a soft grip texture that gently cleans while helping to restore the natural pH of the skin.

Things to Keep in Mind

These are refill wipe packs, meaning you will need to put them into a dispenser to prevent them from drying out.

Who’s it Best for?

Pampers Baby Sensitive Wipes are recommended for infants and babies with sensitive skin and certain skin conditions like diaper rash.

WaterWipes Sensitive Baby Wipes

Best Wipes for Diaper Rash Water Wips

WaterWipes are different than other types of baby wipes. WaterWipes Sensitive Baby Wipes contain 99.9 percent water with just a drop of fruit extract. These wipes are manufactured in Ireland with water sourced from pure Irish spring water.

For diaper rashes, sticky fingers, and dirty faces, WaterWipes offer a fragrance and alcohol free option for cleaning delicate baby skin. They are also suitable for babies with certain skin conditions, such as eczema. In fact, WaterWipes was awarded the National Eczema Association of American Seal of Acceptance.

The wipes cost just under $43 for 12 packs, which make each wipe $0.06. While WaterWipes are not a cure for diaper rash, they do not contain any harsh chemicals or ingredients that will further irritate the skin. You will find grapefruit seed extract (GSE) which acts as a natural skin conditioner, helping keep baby’s skin soft and hydrated.

WaterWipes Sensitive Baby Wipes are free of alcohol, chlorine, perfume, parabens, formaldehyde, phenols, quaternary, phthalates, and other unnecessary additives. The wipes are formed with cotton wool.

Things to Keep in Mind

The manufacturer suggests using the wipes within four weeks of opening the pack. You should also avoid flushing them.

Who’s it Best for?

WaterWipes are gentle enough for newborn skin. They are also idea for babies with skin sensitization problems.

Bamboo Nature Tidy Bottoms Baby Wipes

Best Wipes for Diaper Rash BamboSafe for use on skin from head to toe, Bamboo Nature Tidy Bottoms Baby Wipes offers a gentle and reliable clean without harmful ingredients. Each wipe is made from soft non-woven materials that help grip messes and thoroughly cleanse the skin.

Bamboo baby wipes made the list of best wipes on Lucie’s List, and is popular among parents who value eco-friendly baby care products. The wipes are dermatologically-tested and do not contain parabens, perfumes, chlorine, dyes, or optical brighteners.

Each pack of 50 wipes is approximately $4, or $0.08 per wipe. If you prefer to buy in bulk, Bamboo wipes are also available in 20 packs for just under $80. Want to try them first? The company also offers sample packs.

Things to Keep in Mind

These wipes are slightly smaller than other baby wipes. However, their compact size makes them perfect for your purse or diaper bag.

Who’s it Best for?

Bamboo Nature Tidy Bottoms Baby Wipes are the optimal choice for parents who want an eco-friendly wipe that is affordable and gentle on children’s skin.

Diaper rashes can develop for a number of reasons. It’s how you handle this common issue that makes all the difference. Make the switch to a gentle wipe and help ward off diaper rash.


Brandy Dishaw

Brandy is a content specialist and proud mother of two children. She enjoys writing engaging content on parenting, children’s health, and educational topics, and has been published on websites like Modern Mom, Yahoo! Shine, and With more than a decade of experience as a writer and mom, she combines research and personal experience to provide her audience with insight to the world of parenting.

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